Neffy (Epinephrine Nasal Spray) for Food Allergies

Overview
Neffy is approved by the U.S. Food and Drug Administration (FDA) for the emergency treatment of type one allergic reactions, including anaphylaxis, in adults and children who weigh 30 kilograms (around 66 pounds) or more. Individuals eligible for Neffy treatment typically experience severe allergic reactions to triggers like certain foods, insect stings, or medications. Neffy is also known by its drug name, epinephrine.

Neffy is an alpha/beta-adrenergic receptor agonist. It works by stimulating alpha and beta receptors, which helps to relax muscles in the airways, tighten blood vessels, and reduce swelling during an allergic reaction. This action can rapidly reverse the symptoms of anaphylaxis, such as difficulty breathing and low blood pressure.

How do I take it?
Prescribing information states that Neffy is administered as a single spray into one nostril. If there is no clinical improvement or if symptoms worsen after the initial dose, a second dose may be administered in the same nostril with a new nasal spray, starting five minutes after the first dose. A person should seek emergency medical assistance following administration. Neffy should be used exactly as prescribed by a health care provider.

Side effects
Common side effects of Neffy include throat irritation, intranasal paresthesia (tingling in the nose), headache, nasal discomfort, jitteriness, fatigue, tremor, rhinorrhea (runny nose), nasal itching, sneezing, abdominal pain, gum pain, oral hypoesthesia (reduced sensation in the mouth), nasal congestion, dizziness, nausea, and vomiting.

Rare but serious side effects may include aggravation of heart conditions such as angina pectoris (chest pain) or the development of ventricular arrhythmias (irregular heartbeats), particularly in individuals with existing heart disease.

For more information about this treatment, visit:

Neffy — Drugs.com

FDA Approves First Nasal Spray for Treatment of Anaphylaxis — U.S. Food & Drug Administration